Monday, July 17, 2017

Molecular diagnostic testing.......

Non-invasive testing is preferred now-a-days
Blood based genomic/ molecular diagnostic test for patients in an age of personalized medicine (e.g. small blood sample from the patient;  high-throughput processing in a centralized laboratory; genome, exome, and transcriptome;  protein expression information)
Tests are being developed and submitted to FDA for approval
Host factors (Genes related to cell death, cell signaling, and DNA damage repair) and tolerance (radiation dose, drugs dose)
Multiple genes are activated in circulating blood cells in patients (CRP protein, prolactin, insulin, cortisol etc.)
Gene expression score (GES) diagnostic test can analyze gene expression for diagnosis
of inflammatory disease, arterial blockage
Publication in in peer reviewed journals

Wednesday, July 12, 2017

Gyenic/female ailments: Information and hypotheses.........

Excess androgen causes PCOS (polycystic ovarian syndrome) and insulin resistance
Torsion of cysts can prevent blood flow to the ovary
Dermoid cysts are large, and often contain hair, teeth, bone
Cautery - the act of coagulating blood and destroying tissue with a hot iron or caustic agent or by freezing
Its an approach to deal with polycystic ovarian cysts, if medications can't health them.
Pseudocyesis - false pregnancy
Women with this condition miss menstruation, and have bloated abdomens. Their hormone levels may rise, and their breasts may secrete colostrum.
Cause of high level of hormone can be ovarian cysts, tumors, depression etc.
Female athletes commonly suffer from: amenorrhea (being without a period for three months), decreased bone mineral density, and low energy availability (including disordered eating)
Inflammation is the cause of female reproductive issues. Pollution, chemical additives, cosmetics, fragrance etc. are the culprits